A solemn celebration dedicated to the 77th anniversary of the founding of the Stephan Angeloff Institute of Microbiology - BAS (IMicB) and to the 20th anniversary of its membership in the Pasteur network was held on 7 March at the Institute. The event was opened by Prof. Penka Petrova, Director of IMicB, with a presentation on the Institute's successes, vision and strategy for its development and its place in the Pasteur network. Dr. Cecilia Castillo, responsible for the regional and strategic development of the Pasteur Network in the Euro-Mediterranean region, welcomed the audience and presented the perspectives and directions for the development of the Network as well as opportunities for cooperation. In the "Success stories of Bulgarian scientists in the Pasteur network" session, presentations were [...]

Dr. Radoslav Alexandrov and Assoc. Prof. Stoyno Stoynov PARP inhibitors are anticancer drugs that selectively inhibit the growth of tumors with deficiencies in DNA repair capacity, and are being approved for a growing number of indications. A deeper understanding of the mechanisms of action of PARP inhibitors as well as the function of their target PARP1 represent a hot topic in molecular oncology. Scientists from the Genomic Stability Laboratory and the Sofia Eurobioimaging Center for Advanced Light Microscopy at the Institute of Molecular Biology-BAS (IMB-BAS) are part of a thirteen-member interdisciplinary team that published a study on "PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends" in one of the three most prestigious journals in the world of [...]