Scientists at BAS have developed an innovative method that reveals the movement of chromosomes with unprecedented accuracy

 The paper has received outstanding recognition - it has been selected for the cover of the April issue (2025) of the Nature Cell Biology journal. An all-Bulgarian research team from the “Acad. Roumen Tsanev” Institute of Molecular Biology at BAS published an article in the Nature Cell Biology journal on 14 April 2025. The authors of the study are Rumen Stamatov, Sonya Uzunova, Yoana Kicheva, Maria Karaboeva and Tavian Blagoev, under the supervision of Assoc. Prof. Stoyno Stoynov. The team overcomes long-standing methodological challenges in the study of chromosome dynamics during mitosis, a key process in cell division. Over the course of more than four years, scientists developed an innovative method called FAST CHIMP (Facilitated Segmentation and Tracking of Chromosomes in Mitosis Pipeline). [...]

2025-04-14T16:43:15+03:00Monday, 14 April 2025|Categories: Biomedicine and Quality of Life, Selected|

Scientists discuss the possibilities of tissue engineering and skin modeling at BAS

Recent advances in the refinement of human skin model systems and their possible applications in various fields of biomedicine: this is the hot topic that brought together more than 100 scientists from 28 countries, including the UK, France, Germany, Belgium, Austria, Italy, Spain, Portugal, Finland and Türkiye. For three days, from 26 to 28 February 2025, the Bulgarian Academy of Sciences hosted the fifth meeting of the participants in Action CA 21108 of the European Cooperation in Science and Technology (COST) on the theme: “European Network for Skin Engineering and Modeling (NETSKINMODELS)” involving specialists from 44 countries, including Bulgaria. The skin is not just the largest organ in the human body; it plays a key role in our overall health and well-being. It is the [...]

2025-03-06T09:41:01+02:00Wednesday, 5 March 2025|Categories: Biomedicine and Quality of Life|Tags: |

A new project on the design of innovative polymeric materials as biocontrol agents with application in eco-agriculture is being implemented at IP – BAS

The project BG-RRP-2.011-0005-C01 "Design of Innovative Polymeric Materials as Biocontrol Agents with Application in Eco-Agriculture" (AGROBIOMAT), funded by the European Union - Next Generation EU through the Recovery and Resilience Mechanism for the implementation of the investment under C2I2 "Enhancing the Innovation Capacity of the Bulgarian Academy of Sciences (BAS) in the Field of Green and Digital Technologies" of the Recovery and Resilience Plan, has been launched and is being implemented at the Institute of Polymers - BAS. The main objective of the project is to obtain a range of new and innovative polymeric materials with controlled design suitable as carriers for biocontrol agents with potential application in eco-agriculture. The specific objectives are aimed at applying and combining classical with “green” methods to meet the [...]

2024-07-26T11:32:20+03:00Friday, 26 July 2024|Categories: Biomedicine and Quality of Life|

Success stories of Bulgarian scientists in the Pasteur Network

A solemn celebration dedicated to the 77th anniversary of the founding of the Stephan Angeloff Institute of Microbiology - BAS (IMicB) and to the 20th anniversary of its membership in the Pasteur network was held on 7 March at the Institute. The event was opened by Prof. Penka Petrova, Director of IMicB, with a presentation on the Institute's successes, vision and strategy for its development and its place in the Pasteur network. Dr. Cecilia Castillo, responsible for the regional and strategic development of the Pasteur Network in the Euro-Mediterranean region, welcomed the audience and presented the perspectives and directions for the development of the Network as well as opportunities for cooperation. In the "Success stories of Bulgarian scientists in the Pasteur network" session, presentations were [...]

2024-03-11T16:56:45+02:00Thursday, 7 March 2024|Categories: Biomedicine and Quality of Life, Selected|

Scientists uncover new function of a key protein – target of potent anti-cancer therapy

Dr. Radoslav Alexandrov and Assoc. Prof. Stoyno Stoynov PARP inhibitors are anticancer drugs that selectively inhibit the growth of tumors with deficiencies in DNA repair capacity, and are being approved for a growing number of indications. A deeper understanding of the mechanisms of action of PARP inhibitors as well as the function of their target PARP1 represent a hot topic in molecular oncology. Scientists from the Genomic Stability Laboratory and the Sofia Eurobioimaging Center for Advanced Light Microscopy at the Institute of Molecular Biology-BAS (IMB-BAS) are part of a thirteen-member interdisciplinary team that published a study on "PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends" in one of the three most prestigious journals in the world of [...]

2024-03-06T09:46:36+02:00Tuesday, 5 March 2024|Categories: Biomedicine and Quality of Life, Selected|

ОOfficial closing of the National Scientific Programme ” Innovative low-toxic bioactive systems for precision medicine (BioActiveMed)”

On December 13, 2023, the official closure of the National Scientific Programme "Innovative Low-toxic Bioactive Agents for Precision Medicine (BioActiveMed)" was held in the “Prof. Marin Drinov” Hall of BAS. The presentation was attended by Corr. Memb. Evdokiya Pasheva - Vice-President of BAS, members of the leadership of BAS, members of AACM and representatives of higher education institutions. Mrs. Vesela Vassileva, State Expert at the Science Directorate, read a congratulatory address on behalf of Prof. Galin Tsokov - Minister of Education and Science. The programme is funded by the Ministry of Education and Science and is focused on conducting research to develop new low-toxic biologically active agents and systems containing extracts from natural sources (plant or animal origin) from Bulgaria for the prevention and support [...]

2023-12-18T10:26:59+02:00Thursday, 14 December 2023|Categories: Biomedicine and Quality of Life|
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